Artikel Jurnal
The Relationship between Obesity and Allergies with Olfactory Disorders in Covid-19 Patients
Background : The prevalence of olfactory disorders is around 68–85% which occurs in
COVID-19 patients with obesity and allergies as risk factors. The abnormalities olfactory
pathways can cause by inflammatory response in adipose tissue in obese patients and
excessive inflammation due to hyperreactivity of the immune system to allergens in
allergic patients. This study aims to analyze the relationship between obesity and
allergies to the occurrence of olfactory disorders in COVID-19.
Methods : It was an observational study during pandemic. Subjects were adult COVID-19
patients in the dr. Kariadi Hospital from June to July 2021. Patient with complete medical
record ask for olfactory and allergic questionnaire. Patient with nasal tumor were
excluded.
Results : We found 100 subjects who meet the criteria. There was a significant difference
in smell disturbances between obese and non-obese subjects. (p = 0.019, OR 4.99). There
was a significant difference (p=0.001) in complaints of olfactory disorders between
allergic and non-allergic subjects, whereas all allergic subjects experienced olfactory
disorders.
Conclusion : Obesity and allergies are corelated with impaired smell in COVID-19
patients.
Keywords : COVID-19, olfactory disorders, obesity, allergies
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