Artikel Jurnal
The difference of platelet-white blood cell ratio in severe preeclampsia and normotensive pregnancy
Background: Inflammation is believed to play a role in preeclampsia. Leukocytes increase due to inflammatory response.
Endothelial damage in preeclampsia induces platelet aggregation, triggers platelet consumption, and decreases platelet.
Therefore, preeclampsia could alter the platelet-white blood cell ratio, which can be used as a marker for preeclampsia. This
study examines the difference of platelet-white blood cell ratio in severe preeclampsia and normotensive pregnancy.
Methods: This study used the medical records of pregnant women in Dr. Kariadi General Hospital Semarang from 2019 to
2020. Samples were collected using a consecutive sampling method. Data were analyzed using an independent t-test and
Mann-Whitney.
Results: There was a significant difference in platelet count (p=0.011) and leukocyte count (p=0.018) between severe
preeclampsia and normotensive pregnancy. Therefore, a difference (p
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