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The relationship between nutritional status before chemotherapy with nutritional status after chemotherapy in locoregionally advanced nasopharyngeal carcinoma patients
Background: Malnutrition in nasopharyngeal carcinoma (NPC) patients is caused by various factors such as tumor
localization, metabolic derangement, and side effects of therapy. Poor nutritional status in cancer patients is associated with
serious clinical consequences such as poor quality of life, higher treatment toxicity, and poor prognosis. The purpose of this
study was to determine the effect of nutritional status before chemotherapy on the nutritional status after chemotherapy in
non-metastatic advance-stage NPC patients.
Methods:This study was an observational study with a cross sectional design using secondary data involving non-metastatic
advanced-stage NPC patients undergoing chemotherapy at dr. Kariadi Hospital Semarang in January 2020 – June 2022. The
sampling technique used was consecutive sampling. Nutritional status was measured by malnutrition criteria according to
the American Society for Parenteral and Enteral Nutrition (ASPEN). Statistical analysis was performed with Chi-Square and
McNemar analysis test.
Results: Total sample of this study was 55 subjects. The results of this study were there was a relationship between
nutritional status before chemotherapy and nutritional status after chemotherapy in non-metastatic advanced-stage NPC
patients (P
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