Artikel Jurnal

Correlation of Platelet-To-Lymphocyte Ratio and Troponin I Levels in Patients with ST-Elevation Myocardial Infarction

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Introduction : Platelet and lymphocyte are crucial in acute myocardial infarction (AMI)
pathogenesis. Platelet-lymphocyte ratio (PLR) is a systemic biomarker which indicates
thrombosis and inflammation. The diagnosis of AMI can be made by detecting elevated
blood troponin I levels. The correlation between PLR and troponin I levels in ST-segment
elevation myocardial infarction (STEMI) patients has not been widely known. The
objective of this study is to determine the correlation between PLR and troponin I levels in
STEMI patients.
Methods : This study was a cross-sectional study which data were obtained from the
medical records of patients with STEMI admitted to Dr. Kariadi General Hospital
Semarang from 2019 to 2020. Serum Troponin I levels were measured with EnzymeLinked Fluorescent Assay (ELFA) method in less than 24 hours from symptoms onset.
Complete blood counts were performed immediately on hospital admission. Correlations
between variables were obtained using Spearman's test.
Results : A total of 28 STEMI patients were included, 82.1% were male, mean age was
55.81 ± 2.13 years old. Mean symptoms onset was 7.52 ± 0.81 hours prior to admission.
Mean PLR and troponin I levels were 233.32 ± 25.54 and 14.44 ± 3.16 μg/l, respectively.
A moderately significant correlation was detected between troponin I levels and PLR in
STEMI patients (r=0.333; p=0.042). Symptoms onset in STEMI patients had significant
correlation to troponin I levels (r=0.596; p=0.001).
Conclusion : A moderate positive correlation between PLR and troponin I levels is
observed within 24 hours from symptoms onset in STEMI patients.
Keywords : Platelet-to-lymphocyte ratio; ST-segment elevation myocardial infarction;
troponin I

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Availability

Detail Information

Series Title

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Call Number

616.1 TAM c

Publisher

Semarang : Medica Hospitalia., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

616.1

Content Type

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Media Type

-

Carrier Type

-

Edition

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Subject(s)

Myocardial Infarction
Platelet Count
Lymphocytes

Specific Detail Info

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Statement of Responsibility

Tamariska Evelyn

Viewer

72

Other Information

Tanggal Pelaksanaan - Dari

2024-12-27

Tanggal Pelaksanaan - Sampai

2024-12-27

Akreditasi

Tidak

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