Perbandingan Pengaruh Pemberian Ketamin 0,1mg/KgBB dan Parasetamol 1000 mg Secara Intravena Terhadap Kadar Interleukin-6 Pada Pasien Pasca Lower Limb Orthopedic Surgery

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Perbandingan Pengaruh Pemberian Ketamin 0,1mg/KgBB dan Parasetamol 1000 mg Secara Intravena Terhadap Kadar Interleukin-6 Pada Pasien Pasca Lower Limb Orthopedic Surgery

Taufik Eko Nugroho - Personal Name; Adi Sakti Setionegoro, - Personal Name; Aria Dian Primatika - Personal Name; Satrio Adi Wicaksono - Personal Name;

Background:Breakthrough pain (BTP) is a transient increase in pain that occurs on a background of stable pain. It contributes substantially to the suffering experienced by most cancer patients. The pharmacologic options for management of BTP have been expanded considerably in the past decade. Opioids remain the most effective pharmaceuticals used for the BTP case. In this systematic review we attempted to provide the currently available clinical data about pharmacological treatment for breakthrough cancer pain.Objective:To evaluate the efficacy of pharmacological treatments for Breakthrough painMethods:We searched the Cochrane Central Register of Controlled Trials (CENTRAL) and PubMed for the last ten years (from September 2010 to September 2020. Further potentially relevant studies were identified from reference lists of studies marked for inclusion and relevant reviews. Two review authors independently assessed trial quality and extracted data. We screened the search results and included studies if they met the selection criteria.Result:We screened 205 publications of which 14 met the inclusion criteria.In total, we analysed data from 2129 participants. Overall, participant with BTP were treated with short acting opioid. Literature searching did not find any published evidence of non opioid drug to treat the BTP. Most adverse effects of the investigated drugs seemed to be moderate.Conclusion:The findings of this review suggest that rapid onset opioids play significant role for BTP. Future studies may be conducted to explore the efficacy and safety profiles each regimen for patients with certain categories of cancer.Keywords:breakthrough pain;episodic pain;cancer pain; chronic pain;pharmacological treatment

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Perpustakaan RSUP Dr. Kariadi Semarang 617.4 TAU p

P00395S

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Detail Information

Series Title: -
Call Number: 617.4 TAU p
Publisher: Semarang : Jurnal Anestesiologi Indonesia., 2022
Collation: -
Language: English
ISBN/ISSN: -
Classification: 617.4
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): Ketamine
Interleukin-6
Orthopedic Procedures
Specific Detail Info: -
Statement of Responsibility: Taufik Eko Nugroho
Viewer: 101

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Tanggal Pelaksanaan - Dari: 2024-12-27
Tanggal Pelaksanaan - Sampai: 2024-12-27
Akreditasi: Tidak

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Perbandingan Pengaruh Pemberian Ketamin 0,1mg/KgBB dan Parasetamol 1000 mg Secara Intravena Terhadap Kadar Interleukin-6 Pada Pasien Pasca Lower Limb Orthopedic Surgery

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