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Ameliorative effect of peach gum on metabolic syndrome components and microbial short-chain fatty acids production in streptozotocin-induced rats
Peach gum (PG) contains a large number of polysaccharides and has hypolipidemic and
anti-diabetic properties. Peach gum, specifically, may increase short-chain fatty acids
(SCFAs), which modulate lipid, glucose, and insulin sensitivity and thus improve
metabolic syndrome components (MetS). However, the mechanism remains unclear. This
study aimed to reveal the effects of a whole PG intervention in ameliorating MetS
conditions. Peach gum powder (PGP) was given in three dosages, comprised of PGP-L
(210.64 mg), PGP-M (421.27 mg), and PGP-H (842.55 mg). Initially, PG was ground into
powder (PGP). A total of five groups of Wistar rats were constituted. The healthy group
was fed on a regular feeding (Comfeed AD II). MetS group was given a high-fat diet, a
streptozotocin, and Nicotinamide injection. This study showed PGP significantly
(p
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