Artikel Jurnal

Correlation between Interleukin 10 Serum Levels and Severity of Peripheral Neuropathy in Multibacillary Leprosy Patients a Research Article

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Background:Leprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. Clinical presentations of leprosy neuropathy are obtained when the nerve damage is more than 30% of peripheral nerve fibers. The anti-inflammatory property of interleukin 10 is supposed to protect tissue from the damage caused by proinflammatory cytokines. Instead,it causes extensive nerve damage due to suppression of the cellular immune system, failure of forming granuloma to limit the growth ofMycobacterium leprae. As a result, it multiplies and spreads.Purpose:To analyze the correlation betweeninterleukin levels 10 serum and theseverity of peripheralneuropathy.Methods:A cross-sectional research on 30 subjects with multibacillary leprosy aged 18-65 at the Neurology Department of Kelet Hospital Jepara from September to October 2021. The questionnairewas used to collect data of thepatients. Interleukin level 10 serum evaluation is assessed by examiningblood serum. Data analysis usedSpearman Correlation Test. The significant result occurs if itis p

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Detail Information

Series Title

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Call Number

616.936 FAJ c

Publisher

Semarang : Diponegoro Medical Journal (Jurnal Kedokteran Diponegoro)., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

616.936

Content Type

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Media Type

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Carrier Type

-

Edition

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Subject(s)

Interleukin-10
Peripheral Nervous System Diseases
Leprosy, Multibacillary

Specific Detail Info

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Statement of Responsibility

Fajar Sekti Reliyana

Viewer

91

Other Information

Tanggal Pelaksanaan - Dari

2024-12-31

Tanggal Pelaksanaan - Sampai

2024-12-31

Akreditasi

Tidak

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