Artikel Jurnal
The Outcome of Surgical and Radiotherapy in Central Neurocytoma: A Case Report
Background : Central neurocytoma (CN) is an infrequent and non-malignant neuroepithelial tumor. CN is mostly found in lateral ventricle and may generate obstructive
hydrocephalus. Surgical-radiation can increase patient survival and prognosis. This case
report presented a rare case about 30-year-old female with CN.
Case presentation : 30-year-old female came to the hospital with severe headache and
vomiting. Brain MRI showed a heterogeneous mass in right lateral ventricle causing
obstructive hydrocephalus. The patient undergone partial resection. CN confirmed from
histopathological analysis. Afterward, patient received 54 Gy conventional radiotherapy.
3 months after radiation, patient remain asymptomatic and no neurological deficit. Brain
MRI evaluation showed slightly reduction of tumor mass (from 4.09 x 3.01 x 4.13 cm
before radiation to 4.00 x 3.86 x 3.63 cm after radiation).
Discussion : This case report was consistent clinically, radiologically, and
histopathologically with intraventricular CN. Headache and vomiting in patient due to the
raised intracranial pressure from tumor mass and obstructive hydrocephalus. Headache
is a significant and most frequent symptom in intraventricular tumors, may be caused by
traction or compression of the pain-sensitive structures such as meningen and
intracranial vasculature. Optimal management of CN still remains controversial due to
their rarity. However, surgical management with gross total resection is the gold standard
of treatment modality, associated with good prognosis and longer progression-free
survival.
Conclusion : Based on clinical characteristic, radiographic finding and histopathological
features; this case was consistent with CN of the lateral ventricle. Surgical as the
treatment option followed by radiation has led to good clinical outcome in this patient.
Keywords : central neurocytoma, hydrocephalus, neuro-epethelial tumor, radiotherapy
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