Artikel Jurnal

The Role of Gut Dysbiosis in Malnutrition Mechanism in CKD-5 HD Patients

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Patients with terminal stage chronic kidney disease who have undergone hemodialysis (PGK-5 HD) have a high risk of developing malnutrition, which is characterized by wasting protein-energy and micronutrient deficiencies. Studies show a high prevalence of malnutrition in CKD-5 HD patients. The pathogenic mechanisms of malnutrition in CKD-5 HD are complex and involve the interaction of several pathophysiological changes including decreased appetite and nutrient intake, hormonal disturbances, metabolic imbalances, inflammation, increased catabolism, and abnormalities associated with dialysis action. A clear understanding of the pathophysiological mechanisms involved in the development of malnutrition in CKD-5 HD is required to develop strategies and interventions that are appropriate, effective, and reduce negative clinical outcomes. This article is a review of the pathophysiological mechanisms of malnutrition in CKD-5 HD patients caused by chronic inflammation due to intestinal dysbiosis.

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Availability

Detail Information

Series Title

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Call Number

616.61 EST t

Publisher

Makedonia : Open Access Macedonian Journal of Medical Sciences., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

616.61

Content Type

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Media Type

-

Carrier Type

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Edition

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Subject(s)

Renal Insufficiency, Chronic
Malnutrition
Gastrointestinal Microbiome

Specific Detail Info

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Statement of Responsibility

Esti Widiasih

Viewer

150

Other Information

Tanggal Pelaksanaan - Dari

2024-12-31

Tanggal Pelaksanaan - Sampai

2024-12-31

Akreditasi

Tidak

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