Artikel Jurnal
Case Presentation of 55-YEAR-OLD MAN with acute myeloid Leukemia and Covid 19
Background: Acute myeloid leukemia (AML) is a malignancy from hematopoietic cells, characterized by clonal
proliferation of abnormal blast cells in the bone marrow and failure of average cell production. Coronavirus disease-19
(COVID-19) is a respiratory infectious disease caused by the SARS-CoV-2 virus. COVID-19 infection in AML patients
will affect laboratory examinations to support the diagnosis of COVID-19 and the patient's prognosis. Case
presentation: A 55-year- old man went to the hospital for chemotherapy and was diagnosed of acute myelomonocytic
leukemia. He noted gingival bleeding. The results of the routine haematological examination showed pancytopenia and
the patient requires blood transfusion before chemotherapy. On the third day of treatment, he was experiencing fever,
continued with cough and shortness of breath. Physical examination showed pulse rate 100x/minutes, respiratory rate
26x/minutes, temperature 39.8˚C, crackles of the lungs. RT-PCR examination from the nasopharyngeal swab showed a
positive SARS-CoV-2. During the treatment, the laboratory tests showed pancytopenia, increased of D-Dimer, C-reactive
protein, ferritin and procalcitonin. After the 42
nd day of treatment, the patient had clinical improvement, and the fifth
evaluation swab showed a negative RT-PCR result. Conclusion: AML patients have a higher risk of infection, especially
COVID-19 infection. Correct laboratory examinations and treatment will promote a better prognosis. It is necessary to
educate leukemic patients to always take precautions against infection, especially the prevention of COVID-19.
Keyword : AML COVID-19, SARS-CoV-2
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