Introduction: Viral infection such as coronavirus disease 2019 (COVID-19) can exacerbate and aggravate neurological disorders due to autoimmune etiology like myasthenia gravis (MG). Experimental therapies used in COVID-19 are also factors that can cause the worsening of MG symptoms. This review aimed to assess and conclude the researchbased study systematically to analyze the relationship of M…
Background : Apolipoprotein E (APOE) gene is believed to associate with cholesterol level, a risk factor of ischemic stroke. CIMT (carotid intima-media thickness) can be used to determine the degree of atherosclerosis. Increased CIMT may predict ischemic stroke recurrence. This study aimed to determine association between increased CIMT in post ischemic stroke patients and APOE genotype. M…
Introduction: Risk factors for mortality of critically ill Coronavirus disease 2019 (Covid-19) were older age, use of a mechanical ventilator, high modified nutrition risk in critically ill (mNUTRIC) score, presence of comorbidities, lower body mass index (BMI), acute respiratory distress syndrome (ARDS), and energy deficit in an intensive care unit (ICU). Methods: A retrospective cohort study …
Background: Spinocerebellar ataxia (SCA) is a late onset neurodegenerative disorder in which coordination and balance are affected. Although many international guidelines have been established regarding presymptomatic testing, it is still a grey area in Indonesia. We report two large families with advanced stages of SCA who underwent presymptomatic gene…
Latar belakang : Obstructive Sleep Apnea (OSA) ditandai dengan adanya obstruksi jalan napas yang menyebabkan napas berhenti sesaat, baik secara total maupun parsial. OSA dapat menyebabkan komplikasi yang berat. Diagnostik pasti OSA dengan polisomnografi (PSG). PSG tidak banyak tersedia di fasilitas kesehatan, pemeriksaan friedman tongue position (FTP) diharapkan dapat menjadi pemeriksaan se…
Background:Leprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. Clinical presentations of leprosy neuropathy are obtained when the nerve damage is more than 30% of peripheral nerve fibers. The anti-inflammatory property of interleukin 10 is supposed to protect tissue from the damage caused by proinflammatory cytokines. Instea…
Manajemen pelayanan farmasi terkait dengan potensi fraud pada saat pemberian perbekalan farmasi yang dibutuhkan untuk pelayanan pasien rawat inap. Salah satunya retur perbekalan farmasi pada pasien rawat inap setelah close billing yang tinggi kemudian terjadi penurunan, hal ini berpotensi menjadi bagian dari tindakan fraud. Kejadian fraud pada permasalahan retur perbekalan farmasi di rumah …
Rumah sakit sebagai institusi pelayanan kesehatan berkomitmen pada keselamatan pasien, pengunjung, dan stafnya. Kebutuhan sarana dan prasarana untuk pelayanan dipenuhi melalui proses pengadaan barang dan jasa. Rumah sakit wajib memberikan kepuasan kepada pemasok dalam kerjasama pengadaan barang dan jasa sebagai pelanggan eksternal rumah sakit. Kepuasan pemasok merupakan hal penting bagi ruma…
Background : Thyroid storm is an endocrine disorder emergency which has a high morbidity and mortality rates. The incidence of thyroid storm is seen in less than 10% of all hospitalized thyrotoxicosis patients. However, it has a high mortality rate, which accounts to 20–30% of the cases. It is important to diagnose early to facilitate appropriate immediate management, which can improve pr…
Introduction: Hypoxia fuels cancer growth by supporting blood vessel formation, suppressing immune response, and helping cancer cells adapt to harsh surroundings. This happens when cancer cells react to low oxygen levels by activating hypoxia inducible factor-1 alpha (HIF-1α). High levels of HIF-1α can indicate an aggressive form of cancer and resistance to treatment in diffuse large B-cel…