Latar Belakang: Reseksi hati untuk karsinoma hepatoseluler (HCC) saat ini dikenal sebagai prosedur yang lebih aman daripada sebelumnya karena kemajuan teknis dan perbaikan dalam manajemen pasien pascaoperasi dan tetap menjadi pengobatan lini pertama untuk HCC pada sirosis kompensasi. Hepatektomi adalah strategi pengobatan kuratif yang umum digunakan untuk pa…
Background: Spinal cystic intradural Schwannoma is a type of tumor that is rarely found, with an incidence of 0.3– 0.5/100,000 person per year. The operative procedure for this tumor was simple. However, some patients showed other comorbidities, such as heart failure with low ejection fraction (EF) and atrial fibrillation. Such cases are a challenge to the anaesthesiologist as they are mos…
Background:Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia and associated with several risk factors, such as an unhealthy and unbalanced diet.Porangtubers, known as healthy diet resources, contain glucomannan, a substance that has many positive effects, such as ameliorating blood glucose.Porangtubers are processed as many food products, one of which isporang-proces…
Background:Sepsis is a condition in systemic infection associated with organ dysfunction. Interleukin-17 is a pro-inflammatory cytokine produced by Th-17 cells. C-reactive protein and neutrophil-lymphocyte ratio (NLR) have been widely used as markers of inflammation.The relationship between IL-17 as a proinflammatory cytokine with CRP and NLR has not been reported.Objective: Th…
Background: The current World Health Organization (WHO) 2021 classification of human glioma is based on key molecular biomarkers to define neoplastic entities. This review further delineates mutant IDH (isocitrate dehydrogenase) from wild-type IDH disease, a necessity given the large survival gap between mutant IDH and wild-type IDH tumors. In Indonesia, there are currently few reports on the…
Latar belakang:Epilepsi refrakter merupakan epilepsi yang tidak membaik dengan pemberian obat anti epilepsi yang adekuat. Epilepsi refrakter terjadi pada 30-40% pasien dengan epilepsi. Bedah epilepsi merupakan salah satu tatalaksana dalam epilepsi refrakter, dan penggunaan elektrokortikografi dapat membantu menentukan daerah yang dioperasi. Penggunaan obat-obatan anestesi m…
Backgrounds: Vitamin D regulates muscle function by binding to vitamin D receptors (VDR) via genomic signaling pathways. The biologically active form of vitamin D (1,25- (OH)D) affects muscles by modulation of gene transcription and protein kinase signaling pathways that support proliferation and muscle growth. Aging will result in the interaction of vitamin D and VDR, affecting the regulat…
Background:Sepsis is a systemic disorder as a result of the interaction between the immune system and infectious agents. In some cases, sepsis can progress to septic shock and death. In patients with sepsis with ongoing bacterial contamination, resuscitation may not be successful until control of the source of infection is established. Case:A 47-year-old malewith septic …
Background: Post-operative cognitive dysfunction (POCD) is a decrease in post-operative cognitive abilities that related to patient's health, length of treatment, morbidity, mortality, delay in healing, and decreased quality of life. POCD can occur in 15-25% of patients with surgery, especially in surgery that use general anesthesia. POCD can be diagnosed using a mild co…
Peach gum (PG) contains a large number of polysaccharides and has hypolipidemic and anti-diabetic properties. Peach gum, specifically, may increase short-chain fatty acids (SCFAs), which modulate lipid, glucose, and insulin sensitivity and thus improve metabolic syndrome components (MetS). However, the mechanism remains unclear. This study aimed to reveal the effects of a whole PG intervent…
Background:Breakthrough pain (BTP) is a transient increase in pain that occurs on a background of stable pain. It contributes substantially to the suffering experienced by most cancer patients. The pharmacologic options for management of BTP have been expanded considerably in the past decade. Opioids remain the most effective pharmaceuticals used for th…
Background:Breakthrough pain (BTP) is a transient increase in pain that occurs on a background of stable pain. It contributes substantially to the suffering experienced by most cancer patients. The pharmacologic options for management of BTP have been expanded considerably in the past decade. Opioids remain the most effective pharmaceuticals used for th…
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Histopathological diagnosis has been the gold standard for diagnosing and determining the severity of non-alcoholic steatohepatitis (NASH). However, this method is invasive, especially for diagnosing NASH in children. This research aimed to study the effect of probiotics on the De Ritis ratio, TGF…
Background : Problems of vitamin D deficiency is now starting to become a concern in the world because 1 million people worldwide have vitamin D deficiency and nearly 50% have vitamin D insufficiency. Vitamin D deficiency is more common in neonates and influenced by maternal status which can increase the risk of low birth weight. The aims of this study was to determine the correlation betwe…
Latar belakang : Kemajuan penting telah dicapai dalam upaya menurunkan risiko kejadian kardiovaskular mayor pasien sindroma koroner akut dengan elevasi segmen ST (SKA–ST elevasi) melalui tatalaksana intervensi koroner perkutan (IKP) primer dan perawatan intensif. Walau begitu, kapasitas ruang yang terbatas serta biaya yang tinggi menjadi masalah tersendiri sehingga diperlukan stratifikasi…
Background : Previous studies reported that visceral fat plays an important role in cardiovascular disease, even in non-obese individuals. Bioelectrical impedance analysis (BIA) is a non-invasive and radiation-free method for assessing visceral fat. Not much is known whether visceral fat correlates with lipid profile in myocardial infarction (MI) patients in Indonesian population. The purpo…
Latar belakang : Saat ini, berbagai tanaman asli Indonesia dikembangkan sebagai bahan perawatan luka untuk hasil penyembuhan yang lebih baik. Salah satunya, yaitu Moringa oleifera L., yang merupakan tanaman asli Indonesia serta berpotensi dapat membantu penyembuhan luka melalui regulasi jalur sitokin inflamasi, interleukin (IL)-1 dan IL-10. Penelitian ini bertujuan untuk mengetahui pengaruh…
Introduction : Platelet and lymphocyte are crucial in acute myocardial infarction (AMI) pathogenesis. Platelet-lymphocyte ratio (PLR) is a systemic biomarker which indicates thrombosis and inflammation. The diagnosis of AMI can be made by detecting elevated blood troponin I levels. The correlation between PLR and troponin I levels in ST-segment elevation myocardial infarction (STEMI) patien…
Background: Malnutrition in nasopharyngeal carcinoma (NPC) patients is caused by various factors such as tumor localization, metabolic derangement, and side effects of therapy. Poor nutritional status in cancer patients is associated with serious clinical consequences such as poor quality of life, higher treatment toxicity, and poor prognosis. The purpose of this study was to determine the e…
Background: Breast cancer is a malignancy originating from breast tissue, where chemotherapy is one of the choice therapy. Doxorubicin, 5-fluorouracil, and cyclophosphamide (FAC) are the most commonly used combination of chemotherapy. One of the side effects of chemotherapy is cardiotoxicity. Multiflora honey prevents cardiotoxic effects through its flavonoids and polyphenols compounds. The …